Some test comparisons with the camera-to-subject distance fixed (about 18' or 5 1/2 meters). The white/yellow lure is approximately the size of a small bird. SOOC RAWs, no post processing, tripod mounted, manual exposure and focusing. Full frame images showing uncropped and 100% cropped sections.
RF 200-800 and EF 100-400II both at 400mm:
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View attachment 154892
Now comparing the two with the addition of the EF 1.4xTCIII on the EF100-400II:
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View attachment 154894
To me, the results are
SO close that I would call it a tie. One would have to pixel peep all the time to really worry about it.
Interestingly, the RF 200-800 focuses much better (in terms of accuracy). The 100-400, having a mechanical manual focus ring, has a much coarser/looser focus resolution and is not conducive to fine manual focusing when compared to the 200-800. The slightest bump on the ring can knock the focus off the target. Even with spot AF with the R5 and on a tripod, the EF100-400 showed slight back-focusing by just a fraction of an inch (the 200-800 nailed it every time). However in terms of speed of AF, I imagine that the EF100-400 would be faster to acquire the subject because the focus resolution/sensitivity is coarser (although the 200-800 is still
very fast - enough for many BIF situations).